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The kind you smoke does make a difference in how long they will remain fresh

METHODS Data We pooled data from the 20142018 National Health Interview Survey, an annual cross-sectional household surveys representative of the US non-institutionalized population that capture health behaviors and health status measures including tobacco use and psychological distress 8

Inflammation and the gut-brain connection Cigarette smoke increases low-grade inflammation in the intestines. Since IBS is strongly influenced by the gut-brain axis (the two-way communication between the gut and the nervous system), this extra stress can worsen how signals are processed, leading to more discomfort and unpredictability